Composition and treatment with biologically active peptides...

Details Composition and treatment with biologically active peptides... Composition and treatment with biologically active peptides...

A - Human Necessities

61

K

167/103

A61K 38/00 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01) C07K 14/46 (2006.01)

Patent

CA 2013738

ABSTRACT OF THE DISCLOSURE A composition comprising at least one biologically active amphiphilic peptide, said peptide being an ion channel-forming peptide, and an antibiotic selected from the class consiting of bacitracins, aminoglycosides, penicillins, monobactams, hydrophobic antibiotics, 50-S ribosome inhibitors, antibiotics having a large lipid-like lactone rings and derivatives or analogues thereof. The biologically active amphiphilic peptide and the antibiotic may be administered in amounts effective to inhibit growth of a target cell. The biologically active amphiphilic peptide and antibiotic may potentiate each other.

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