Composition and use of rar antagonists for promoting...

A - Human Necessities – 61 – K

Patent

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A61K 31/202 (2006.01) A61K 31/192 (2006.01) A61K 31/196 (2006.01) A61K 31/203 (2006.01) A61K 31/235 (2006.01) A61K 31/351 (2006.01) A61K 31/352 (2006.01) A61K 31/381 (2006.01) A61K 31/382 (2006.01) A61K 31/655 (2006.01) A61K 31/665 (2006.01) A61K 45/06 (2006.01) A61P 19/02 (2006.01) A61P 19/08 (2006.01)

Patent

CA 2349555

The invention provides compositions comprising a RAR antagonist for promoting chondrogenesis and to methods employing such compositions for treating cartilage and associated bone abnormalities resulting from injury or disease and for ex vivo tissue engineering.

La présente invention concerne des compositions comprenant un antagoniste des récepteurs RAR de façon à favoriser la chondrogenèse. L'invention concerne également l'utilisation de telles compositions, d'une part pour soigner des cartilages ainsi que des anomalies osseuses associées provoquées par des lésions ou des affections, et d'autre part pour des activités de génie tissulaire ex vivo.

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