Composition apparatus and method for use in imaging

G - Physics – 21 – G

Patent

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G21G 1/00 (2006.01) A61K 49/06 (2006.01) A61K 51/00 (2006.01) A61M 36/00 (2006.01) G01N 33/60 (2006.01) G01T 1/164 (2006.01) G21G 1/06 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2660425

In one embodiment, a composition comprises a microparticle including a radioactive isotope and an imageable element. In another embodiment, a method includes forming a microparticle including a target isotope and an enriched paramagnetic isotope, and transforming the target isotope into a radioactive isotope. In yet another embodiment, an apparatus includes an imaging system to image a subject; and a radioactive microparticle suitable for infusion into the subject for imaging by the imaging system and including an enriched paramagnetic isotope that is enriched to reduce generation of radioactive impurities while maintaining or improving imaging sensitivity.

L'invention concerne, selon une de ses réalisations, une composition qui comprend une microparticule incluant un isotope radioactif et un élément visible par des moyens d'imagerie. Dans une autre de ses réalisations, elle concerne une méthode comprenant la formation d'une microparticule incluant un isotope cible et un isotope paramagnétique enrichi, et la transformation de l'isotope cible en un isotope radioactif. Dans encore une autre réalisation, elle concerne un appareillage incluant un système d'imagerie afin de générer une image d'un sujet; et une microparticule radioactive pouvant être diffusée dans le sujet pour la génération d'une image par le système d'imagerie et incluant un isotope paramagnétique enrichi qui est enrichi pour réduire la production d'impuretés radioactives tout en conservant ou améliorant la sensibilité d'imagerie.

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