Composition based on amino acids intended for the treatment...

A - Human Necessities – 61 – K

Patent

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A61K 38/01 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01)

Patent

CA 2134380

Compositions and methods intended to be administered enterally or parenterally for treating sepsis. The composition containing, in a biologically and nutritionally acceptable medium, at least free cysteine or cysteine in the form of a precursor, prodrug, protein or peptide hydrolysate, in a proportion of pharmacologically active cysteine greater than the proportion of cysteine present in a nutritional composition corresponding to the requirements of a healthy man, the proportion of cysteine being determined with respect to all the amino acids present in the composition.

L'invention porte sur des méthodes et des compositions conçues pour être administrées par voie entérique ou parentérale pour traiter la septicémie. La composition contient, dans un milieu biologiquement et nutritionellement acceptable, au moins de la cystéine libre ou non sous forme d'un précurseur, d'un promédicament, d'une protéine ou d'un hydrolysat de peptides. La proportion de cette cystéine pharmacologiquement active est supérieure à la proportion de cystéine présente dans la composition nutritionnelle correspondant aux besoins d'une personne en bonne santé, la proportion de cystéine étant déterminée en fonction de tous les acides aminés présents dans la composition.

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