A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/397 (2006.01) A61K 31/22 (2006.01) A61K 31/35 (2006.01) A61K 31/365 (2006.01) A61K 31/40 (2006.01) A61K 47/08 (2006.01)
Patent
CA 2493076
The instant invention provides a pharmaceutical composition comprised of a cholesterol absorption inhibitor and an HMG-CoA reductase inhibitor, one or more anti-oxidants, microcrystalline cellulose, hydroxypropyl methylcellulose, magnesium stearate and lactose. The composition need not contain ascorbic acid in order to obtain desirable stability.
L'invention concerne une composition pharmaceutique comprenant un inhibiteur de l'absorption du cholestérol et un inhibiteur de la HMG-CoA réductase, un ou plusieurs antioxydants, de la cellulose microcristalline, de l'hydroxypropylméthylcellulose, du stéarate de magnésium et du lactose. Cette composition présente une stabilité suffisante sans adjonction d'acide ascorbique.
Cho Wing-Kee Philip
Fitzpatrick Shaun
Moore William D.
Petts Catherine R.
Saklatvala Robert
Merck Sharp & Dohme Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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