Composition comprising and method of using angiopoietin-like...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) C07K 14/515 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2464542

The present invention is directed to methods and means for making and using Angptl3 polypeptides. The invention specifically concerns the use of Angptl3 polypeptides in inducing liver regeneration and angiogenesis. Further methods include the use of Angptl3 polypeptides in the diagnosis and treatment of liver disease. Also provided herein are antibodies which bind to the polypeptides of the present invention.

L'invention concerne des procédés et des moyens de préparation et d'utilisation de polypeptides Angptl3. L'invention concerne en particulier l'utilisation de polypeptides Angptl3 d'induction de l'angiogénèse et de la régénération du foie. D'autres méthodes consistent à utiliser des polypeptides Angptl3 dans le diagnostic et dans le traitement de maladies du foie. L'invention concerne également des anticorps qui se lient aux polypeptides de l'invention.

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