Composition comprising .beta.-hydroxy-.beta.-methylbutyric...

Details Composition comprising .beta.-hydroxy-.beta.-methylbutyric... Composition comprising .beta.-hydroxy-.beta.-methylbutyric...

A - Human Necessities

61

K

A61K 31/198 (2006.01) A61K 31/19 (2006.01) A61K 31/22 (2006.01) A61K 31/365 (2006.01) A61P 3/02 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2334761

The present invention provides a composition comprising HMB and at least one amino acid. The present invention also provides a method for the treatment of disease-associated wasting of an animal, a method for decreasing the serum-level of triglycerides of an animal, a method for decreasing the serum viral load of an animal, a method for redistributing fat in an animal having a visceral region and a subcutaneous region, a method for increasing the lean tissue mass of an animal without substantially decreasing the fat mass of the animal, and a method for increasing the HDL cholesterol-level of an animal. All methods comprise administering to the animal a composition comprising HMB and at least one amino acid.

L'invention concerne une composition comprenant de l'acide beta -hydroxy- beta -méthylbutyrique (HMB) et au moins un amino-acide. La présente invention concerne également une méthode de traitement de la fonte musculaire d'un animal liée à la maladie, une méthode permettant de réduire le taux sérique des triglycérides d'un animal, une méthode de réduction de la charge virale sérique d'un animal, une méthode de redistribution des graisses dans un animal ayant une zone viscérale et un zone sous-cutanée, une méthode permettant d'accroître la masse maigre d'un animal sans réduction sensible de sa masse adipeuse, et une méthode permettant d'accroître le niveau de cholestérol HDL chez un animal. Toutes ces méthodes impliquent l'administration d'une composition comprenant de l'acide beta -hydroxy- beta -méthylbutyrique et au moins un amino-acide à l'animal.

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