Composition comprising finely divided, crystalline particles...

A - Human Necessities – 61 – K

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Details

A61K 9/16 (2006.01) A61K 9/14 (2006.01) A61K 31/52 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2290538

The invention provides finely divided, substantially crystalline particles of budesonide characterised in that they are substantially smooth and having a BET value from 1 to 4.5 m2/g, process for their preparation, a pharmaceutical composition comprising said particles, the use of said particles in the treatment of and in the manufacture of a medicament for use in the treatment of a respiratory disorder, and a method of treatment of respiratory disorders by administration, to a host in need of such treatment, said particles.

L'invention concerne des particules de budesonide sensiblement cristallines, finement divisées caractérisées en ce qu'elles sont sensiblement lisses et ont une valeur BET comprise entre 1 et 4,5 m<2>/g. L'invention concerne également leur procédé de préparation, une composition pharmaceutique les contenant, l'utilisation de ces particules dans le traitement de troubles préparatoires et la production d'un médicament destiné à ce traitement, et un procédé de traitement de troubles respiratoires par administration de ces particules à un hôte nécessitant un tel traitement.

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