Composition comprising isoorientin for suppressing histamine

A - Human Necessities – 61 – K

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Details

A61K 31/7032 (2006.01) A61K 31/352 (2006.01) A61K 36/899 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2601046

The present invention relates to a pharmaceutical composition for the prevention or treatment of diseases mediated by excessive histamine comprising naturally-derived isoorientin, a use of isoorientin for the manufacture of a medicament for the prevention or treatment of diseases mediated by excessive histamine, and a method for preventing or treating diseases mediated by excessive histamine comprising administering a therapeutically effective amount of isoorientin to a subject. The composition, use and method of the present invention show excellent histamine suppression effects, and so can be used for the prevention or treatment of various kinds of allergic disease, atopic disease, inflammatory disease, skin disease, hyperacidity and nervous system disorder.

Cette invention concerne une composition pharmaceutique servant à prévenir ou à traiter des maladies induites par un excès d'histamine et comprenant de l'isoorientine dérivée naturellement, une utilisation de l'isoorientine dans la fabrication d'un médicament servant à prévenir ou à traiter des maladies induites par un excès d'histamine, ainsi qu'une méthode de prévention et de traitement de maladies induites par un excès d'histamine consistant à administrer une quantité thérapeutiquement efficace d'isoorientine à un sujet. La composition, l'utilisation et la méthode de cette invention présentent d'excellents effets de suppression d'histamine et peuvent ainsi être utilisées pour prévenir ou traiter divers types de maladies allergiques, de maladies atopiques, de maladies inflammatoires, de maladies cutanées, d'hyperacidités et de troubles du système nerveux central.

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