C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) A61K 35/74 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2686393
Disclosed is a lactic acid bacterium having a high and stable anti-allergic activity, which can be used effectively in various forms in various use applications. Specifically, a bacterium Lactobacillus paracasei strain KW3110 or a mutant thereof is subjected to heat treatment at a temperature not lower than 60°C and lower than 100°C for a period not shorter than 10 minutes and shorter than 60 minutes to increase the anti-allergic activity of the lactic acid bacterium dramatically and also stabilize the anti-allergic activity. By the heat treatment, it becomes possible to provide an anti-allergic composition comprising, as an active ingredient, a cell of a lactic acid bacterium having a dramatically increased and stable anti-allergic activity, in which the anti-allergic activity of the lactic acid bacterium is dramatically increased.
L'invention porte sur une bactérie à acide lactique ayant une activité anti-allergique élevée et stable qui peut être utilisée de façon efficace dans diverses formes dans diverses applications d'utilisation. De façon spécifique, une bactérie de la souche Lactobacillus paracasei KW3110 ou un mutant de celle-ci est soumise à un traitement thermique à une température allant de 60°C à 100°C pendant une durée allant de 10 à 60 minutes pour augmenter l'activité anti-allergique de la bactérie à acide lactique de façon spectaculaire ainsi que pour stabiliser l'activité anti-allergique. Le traitement thermique permet de proposer une composition anti-allergique dont le principe actif est la cellule d'une bactérie à acide lactique pourvue d'une activité anti-allergique accrue de façon importante et stable, et dont l'activité anti-allergique est décuplée.
Awayama Hitoshi
Nishida Takeo
Kirin Holdings Kabushiki Kaisha
Smart & Biggar
LandOfFree
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