Composition comprising oil drops

Details Composition comprising oil drops Composition comprising oil drops

A - Human Necessities

61

K

A61K 9/16 (2006.01) A01N 25/04 (2006.01) A61K 38/13 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2762179

A composition comprises a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising an active principle. The invention includes embodiments in which the active principle is included in at least some of the oil droplets as well as embodiments in which the oil droplets are free of active principle. The oil droplets are released as the matrix containing them dissolves in an aqueous medium. In one embodiment, the oil droplets are substantially immobilized in or by the matrix and the immobilizing feature is lost as the matrix dissolves in aqueous media. In certain embodiments, the oil drops may collectively be referred to as the oil phase of the composition of the invention. The product may be in the form of mini-beads. The oil phase and/or the polymer matrix may each include a surfactant.

L'invention concerne une composition qui comprend une matrice polymère hydrosoluble dans laquelle sont dispersées des gouttelettes d'huile, et cette composition comporte un principe actif. Selon des variantes de l'invention, ledit principe est incorporé à au moins une partie des gouttelettes, et selon d'autres variantes ces gouttelettes sont dépourvues de principe actif. Les gouttelettes sont libérées lorsque la matrice qui les contient se dissout dans un milieu aqueux. Selon une variante elles sont sensiblement immobilisées dans ou par la matrice et la fonction d'immobilisation est perdue lorsque la matrice se dissout dans des milieux aqueux. Selon certaines variantes, les gouttes d'huile peuvent être désignées collectivement comme étant la phase huileuse de la composition décrite. Le produit peut se présenter sous la forme de mini-perles. On peut trouver un tensioactif dans la phase huileuse et/ou la matrice polymère.

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