Composition comprising paracetamol and a bitterness masking...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/167 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 33/08 (2006.01) A61K 47/00 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/44 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2463016

A pharmaceutical composition comprising paracetamol and a masking component which reduces or masks the bitter taste thereof which comprises at least two members chosen from the following groups i to vi : i. pharmacologically acceptable magnesium salt, magnesium oxide and/or magnesium hydroxide; ii. gingerin and/or ginger oil; iii. a delayed onset long lasting sweetener; iv. soluble starch in a weight ratio of at least 1:15 with respect to the paracetamol; v. an edible emulsifier having an HLB of greater than 10; and vi. glycine.

Composition pharmaceutique contenant paracétamol et un constituant de masquage réduisant ou masquant le goût amer de la composition et comprenant au moins deux éléments sélectionnés dans les groupes suivants : (i) sel de magnésium acceptable sur le plan pharmacologique, un oxyde et/ou un hydroxyde de magnésium ; (ii) une oléorésine et/ou essence de gingembre ; (iii) un édulcorant à durée prolongée et effet retard ; (iv) de l'amidon soluble dont le rapport de poids est d'au moins 1 :15 par rapport au paracétamol ; (v) un émulsifiant comestible dont le HLB est supérieur à 10 et (vi) glycine.

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