Composition comprising vlp and amyloid-beta peptide

Details Composition comprising vlp and amyloid-beta peptide Composition comprising vlp and amyloid-beta peptide

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2581300

The present invention relates to novel uses of a construct consisting of virus- like particle (VLP) structure chemically coupled to a fragment of the A~-1-42 peptide and its pharmaceutically acceptable salts (hereinafter CONSTRUCT), in particular to dosage regimens, modes of and dosage forms for the administration of a CONSTRUCT for the treatment of patients suffering from dementia, in particular dementia of the Alzheimer's type.

La présente invention se rapporte à de nouvelles utilisations d'un produit de synthèse possédant une structure de pseudo-particule virale (VLP) couplée par voie chimique à un fragment du peptide A.beta.-1-42, et de ses sels pharmaceutiquement acceptables. L'invention a trait en particulier à des posologies, à des modes d'administration d'un tel produit de synthèse et à des formes posologiques destinées à l'administration d'un tel produit de synthèse pour traiter des patients atteints de démence, en particulier de la démence de type Alzheimer.

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