Composition comprising xanthoceras sorbifolia extracts,...

C - Chemistry – Metallurgy – 07 – J

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C07J 63/00 (2006.01) A61K 31/56 (2006.01) A61K 36/77 (2006.01) A61P 35/00 (2006.01) C07H 17/04 (2006.01) A61K 31/05 (2006.01) A61K 31/35 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2541425

This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia. The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, saponins, tannins, acid, flavonoids and others. The composition can be used for anti- cancer, preventing cerebral aging, improving memory, improving cerebral functions and curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer~s disease, autism, brain trauma, Parkinson~s disease and other diseases caused by cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud~s syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder and treating impotence and premature ejaculation. This invention provides compounds comprise a sugar, terepene, such as Sapogenin, and a side chains at Carbon 21 and 22, such as Angeloyl groups. The compounds of the present have various pharmaceutical and therapeutic applications.

La présente invention concerne des compositions, des procédés et un processus de production d'extraits de Xanthoceras sorbifolia. L'extrait comprend des alcaloïdes, des coumarines, des saccharides, des protéines, des polysaccharides, des glycosides, des saponines, des tannines, de l'acide, et des flavonoïdes, entre autres. La composition peut être utilisée comme agent anticancéreux, pour prévenir le vieillissement cérébral, améliorer la mémoire, améliorer les fonctions cérébrales et guérir l'énurésie, les mictions fréquentes, l'incontinence urinaire, la démence, le manque d'intelligence et la maladie d'Alzheimer, l'autisme, les traumatismes cérébraux, la maladie de Parkinson et autres maladies entraînées par des dysfonctionnements cérébraux, pour traiter l'arthrite, les rhumatismes, la mauvaise circulation sanguine, l'artériosclérose, le syndrome de Raynaud, l'angine de poitrine, les troubles cardiaques, les maladies coronariennes, les maux de tête, les vertiges, les troubles rénaux, l'impuissance et l'éjaculation précoce. L'invention porte sur des composés comprenant un sucre, un terpène, tel que la sapogénine, et une chaîne latérale sur les carbones 21 et 22, par exemple des groupes angeloyle. Les composés de l'invention ont diverses applications pharmaceutiques et thérapeutiques.

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