A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/635 (2006.01) A61K 9/08 (2006.01) A61K 31/4045 (2006.01) C07D 209/30 (2006.01)
Patent
CA 2247329
The present invention provides a preparation for injection comprising an antitumor agent which is sparingly soluble in water. Specifically, it provides a composition containing N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzenesulfonamide, which contains N-(3-chloro-1H-indol-7-yl)-4- sulfamoylbenzenesulfonamide and a basic substance and will provide an aqueous solution having a pH of 7 or higher when dissolved in water.
L'invention a trait à une solution à administration parentérale comportant un agent antitumoral peu soluble dans l'eau, une composition, en l'occurrence, contenant N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzènesulfonamide ainsi qu'une substance de base et dont le pH en solution est égal ou supérieur à 7.
Ando Hidenobu
Ashizawa Kazuhide
Eisai Co. Ltd.
Eisai R&d Management Co. Ltd.
Smart & Biggar
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