Composition containing fine particles for carrying...

C - Chemistry – Metallurgy – 08 – L

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Details

C08L 77/04 (2006.01) A61K 9/10 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C08L 71/02 (2006.01)

Patent

CA 2458837

Provided are a dispersion comprising organic-inorganic hybrid type particles carried thereon with a biologically active substance, wherein the above particles can be obtained by allowing a block copolymer represented by Formula (I): PEG-block-poly(carbo) (I) (wherein PEG represents a polyethylene glycol segment, and carbo represents a repetitive unit having a carboxylate ion on a side chain) and an aqueous medium system capable of forming hydroxyapatite to coexist with the biologically active substance, and a preparing method for the same.

Cette invention concerne une dispersion renfermant des particules hybrides organiques/inorganiques supportant un principe biologiquement actif. Cette dispersion s'obtient en faisant coexister ledit principe actif avec un système comprenant un copolymère bloc représenté par la formule générale (I) : PEG bloc-poly-carbo (dans laquelle PEG représente un segment polyéthylène glycol, et carbo une unité récurrente comportant un coaboxylate dans une chaîne latérale) ; et un support aqueux capable de former une hydroxyapatite.

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