Composition containing heparin or derivative thereof

Details Composition containing heparin or derivative thereof Composition containing heparin or derivative thereof

A - Human Necessities

61

K

167/199

A61K 31/725 (1990.01) A61K 31/73 (1990.01)

Patent

CA 1318591

ABSTRACT: The invention relates to means for preventing or for delaying the rejection of allografts in humans and for the alleviation of and for treating autoimmune diseases in humans. The pharmaceutical compositions which are suitable to attain the above ends are based on heparin, on N-desulfated, N-acetylated heparin, O-desulfated, N-acetylated heparin or other suitable derivatives of heparin. The dosage which is effective is one which is substantially lower than that required for obtaining an anticoagulant effect in mammals. It is generally of the order of about 0.5 per cent to about 5 per cent of the anti-coagulant effective dosage of such compounds.

540717

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