Composition containing nanoparticles containing...

A - Human Necessities – 61 – K

Patent

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A61K 9/51 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61P 5/10 (2006.01) A61P 5/14 (2006.01) A61P 5/24 (2006.01) A61P 25/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2537802

A drug and an in vivo degradable polymer having at least one carboxy group are encapsulated together in each of nanoparticles formed from a block copolymer comprising a hydrophilic polymer segment and a hydrophobic segment. The drug- containing nanoparticles have enhanced in vivo drug stability.

La présente invention concerne un médicament et un polymère dégradable in vivo possédant moins un groupe carboxy, qui sont encapsulés dans chacune des nanoparticules formées à partir d'un copolymère bloc comprenant une partie polymère hydrophile et une partie hydrophobe. Ces nanoparticules contenant un médicament possèdent une stabilité de médicament in vivo renforcée.

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