C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 31/513 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2374941
The invention concerns a composition for implementing an antitumoral or antiviral treatment in a mammal comprising: (i) a nucleic acid sequence coding for all or part of polypeptide p53; (ii) at least a nucleic acid sequence coding for all or part of a polypeptide having at least a cytotoxic activity, said nucleic acid sequences being placed under the control of elements required for their expression in a host cell of said mammal.
La présente invention concerne une composition destinée à la mise en oeuvre d'un traitement antitumoral ou antiviral chez un mammifère comprenant: (i) une séquence d'acide nucléique codant pour tout ou partie du polypeptide p53, (ii) au moins une séquence d'acide nucléique codant pour tout ou partie d'un polypeptide ayant au moins une activité cytotoxique, lesdites séquences d'acide nucléique étant placées sous le contrôle des éléments nécessaires à leur expression dans une cellule hôte dudit mammifère.
Erbs Philippe
Jund Richard
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Transgene
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