Composition, device and method for enhanced electrotransport...

A - Human Necessities – 61 – K

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A61K 47/10 (2006.01) A61K 9/00 (2006.01) A61K 31/4468 (2006.01) A61K 38/28 (2006.01) A61P 3/10 (2006.01) A61P 29/02 (2006.01) A61N 1/18 (2006.01) A61N 1/30 (2006.01)

Patent

CA 2202137

An electrotransport composition comprises at least one C2-C4 lower alcohol, unsaturated derivatives thereof, or mixtures thereof, and at least one C8-C14 higher alcohol, unsaturated derivatives thereof, or mixtures thereof. An electrotransport device and a method of increasing transdermal electrotransport flux utilize the composition of the invention for delivering pharmaceutically-acceptable agents across a body surface such as skin.

La présente invention concerne une composition pour électrotransport, qui comprend au moins un alcool inférieur C2-C4, des dérivés non saturés de celui-ci ou des mélanges de ces composés, et au moins un alcool supérieur C8-C14, des dérivés non saturés de ce dernier ou des mélanges de ces composés. Un appareil d'électrotransport et un procédé d'augmentation du débit de l'électrotransport transcutané utilisent la composition de l'invention pour l'administration d'agents acceptables du point de vue pharmaceutique à travers une surface corporelle telle que la peau.

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