Composition for and method of preventing or treating breast...

Details Composition for and method of preventing or treating breast... Composition for and method of preventing or treating breast...

A - Human Necessities

61

K

A61K 31/7048 (2006.01) A61K 31/135 (2006.01) A61K 31/352 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2310294

The present invention relates to compositions and methods for treating and preventing breast cancer. A method for treating breast cancer is provided in which tamoxifen and an isoflavone are coadministered to a woman having breast cancer. The tamoxifen is administered to prevent, minimize, or reverse the development or growth of the breast cancer. The isoflavone is administered to prevent or minimize tamoxifen induced uterotrophic effects, and preferably, endometrial cancer. Most preferably, administration of the isoflavone enhances the prevention, minimization, or reversal of the breast cancer. In another aspect, tamoxifen and an isoflavone are coadministered to woman predisposed to breast cancer to prevent breast cancer. A composition in accordance with the present invention contains tamoxifen in an amount sufficient to prevent, minimize, or reverse the development or growth of breast cancer and an isoflavone in an amount sufficient to prevent or minimize tamoxifen induced uterotrophic effects, and preferably in an amount sufficient to prevent or minimize endometrial cancer.

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