Composition for aqueous stabilization of fat-soluble vitamins

A - Human Necessities – 61 – K

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Details

A61K 47/18 (2006.01) A61K 9/107 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2420130

Composition for the aqueous stabilization of fat-soluble vitamins that comprises: (i) an alcohol with 4 to 8 carbon atoms (ii) 0.5 to 3 mass unit of amine or amide having 2 to 8 carbon atoms calculated for a unity mass of alcohol; and/or (iii) 1.5 to 6 mass unit of carboxylic acid with 8 to 18 carbon atoms calculated for a unity mass of alcohol. The composition is used in stabilized pharmaceutical or veterinary preparations having an aqueous medium.

L'invention concerne une composition de stabilisation aqueuse de vitamines liposolubles, comprenant (i) un alcool avec 4 à 8 atomes de carbone, (ii) de 0,5 à 3 unités de masse d'une amine ou d'un amide avec 2 à 8 atomes de carbone pour une masse unitaire d'alcool, et/ou (iii) de 1,5 à 6 unités de masse d'un acide carboxylique avec 8 à 18 atomes de carbone pour une masse unitaire d'alcool. Cette composition est utilisée dans des préparations pharmaceutiques ou vétérinaires stabilisées comprenant un milieu aqueux.

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