Composition for controlled release of an active substance...

Details Composition for controlled release of an active substance... Composition for controlled release of an active substance...

A - Human Necessities

61

K

A61K 47/36 (2006.01) A61K 9/20 (2006.01) A61K 9/26 (2006.01)

Patent

CA 2139494

Composition for delayed release of an active substance, such as a medicament, the active substance being incorporated in a polysaccharide matrix which is formed by an essentially crystalline straight-chain glucan, in particular an .alpha.-glucan which has a helix structure, such as amylodextrin or a fraction having a helix structure obtained from amylose V. The composition can con- tain an amount of active substance of from 0.1 to 80 % by weight and the active substance can, depending on the hydrophilicity, have a molecular weight of up to 500 or 1500 daltons. The active substance is released from the composition at a constant rate.

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