Composition for delivery of toxic radioisotopes to the cell...

Details Composition for delivery of toxic radioisotopes to the cell... Composition for delivery of toxic radioisotopes to the cell...

A - Human Necessities

61

K

A61K 51/10 (2006.01) A61K 47/48 (2006.01) A61K 51/08 (2006.01)

Patent

CA 2189051

A conjugate of a tumor cell-targeting protein or polypeptide and a nucleic acid-targeting small molecule labeled with an Auger electron-emitting radionuclide is useful for tumor therapy. The tumor cell-targeting protein or polypeptide may be an antibody or fragment thereof, a hormone or a growth factor.

Conjugué d'une protéine ou d'un polypeptide de ciblage de cellules tumorales et d'une petite molécule de ciblage de l'acide nucléique marquée à l'aide d'un radionucléide émettant des électrons Auger, utile dans la thérapie des tumeurs. Cette protéine ou ce polypeptide peut être un anticorps ou un fragment de celui-ci, une hormone ou un facteur de croissance.

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