C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/04 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 1/107 (2006.01) C07K 14/00 (2006.01) C07K 14/075 (2006.01) C07K 14/095 (2006.01) C07K 14/11 (2006.01) C07K 14/15 (2006.01) C07K 14/16 (2006.01) C07K 14/56 (2006.01) C07K 14/79 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C12N 15/11 (2006.01) C12N 15/87 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2118816
A composition for the transfection of higher eucaryotic cells, comprising a complex of nucleic acid and a substance having an affinity far nucleic acid, optionally conjugated with an internalizing factor for these cells. The composition contains an endosomolytic agent which is either a free or hound virus or a virus component or a viral or non-viral peptide with endosomolytic properties.
Birnstiel Max L.
Cotten Matthew
Curiel David
Oberhauser Bernd
Plank Christian
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
Genentech Inc.
Genetech Inc.
The University Of North Carolina At Chapel Hill
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