Composition for modulating the expression of cell adhesion...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/16 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2656347

A composition is provided for modulating or attenuating the cytokine induced cell surface expression of cell adhesion molecules, comprising an antibody that binds digoxin. There is also provided a method of modulating or attenuating the cytokine induced cell surface expression of a cell adhesion molecule in a patient by administering a digoxin antibody composition to a patient in need of such treatment.

L'invention concerne une composition servant à moduler ou à atténuer l'expression de surface cellulaire induite par une cytokine de molécules d'adhérence cellulaire, ladite composition comprenant un anticorps se liant à digoxine. Elle concerne également un procédé de modulation ou d'atténuation de l'expression de surface cellulaire induite par une cytokine d'une molécule d'adhérence cellulaire chez un patient, ce qui consiste à administrer à celui-ci une composition contenant un anticorps de digoxine..

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