Composition for oral administration containing pyridazinone...

A - Human Necessities – 61 – K

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A61K 31/50 (2006.01) A61K 9/20 (2006.01) A61K 9/30 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2228078

A composition for oral administration which contains a pyridazinone compound of the formula (I) Image wherein R1, R2 and R3 are each independently a hydrogen atom or a lower alkyl, X is a halogen atom, a cyano or a hydrogen atom, Y is a halogen atom, a trifluoromethyl or a hydrogen atom, and A is a C1-C8 alkylene optionally substituted by hydroxy, or a pharmacologically acceptable salt thereof, and an organic acid. According to the present invention, a composition for oral administration which is stable to heat, light, moisture and the like and which shows improved dissolution and absorption of a pyridazinone compound can be provided.

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