Composition for organ cryopreservation and treatment of...

A - Human Necessities – 01 – N

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A01N 37/18 (2006.01) A01N 1/02 (2006.01) A61K 31/16 (2006.01) A61K 39/42 (2006.01)

Patent

CA 2240131

The invention provides a method for the cryopreservation of organs and the treatment of viral and/or microbial infections, the substance or composition comprising an active agent selected from the group consisting of amides of the general formula R3-CO-NR1R2, in which: R1 and R2 are independently selected from the group including H, Me, halomethyl, saturated and unsaturated C2-C3 alkyl groups, saturated and unsaturated halogenated C2-C3 alkyl groups, hydroxylated alkyl groups; or R1 and R2 are together selected from (CH2)n, wherein n = 4 or 5, or (CH2)2O(CH2)2; and R3 is selected from H, Me and saturated an unsaturated C2-C3 alkyl groups.

Cette invention concerne un procédé de cryopréservation d'organes et de traitement des infections virales et/ou bactériennes à l'adie d'une substance ou d'une composition comprenant un agent actif sélectionné dans le groupe constitué par des amides de formule R¿3?-CO-NR¿1?R¿2?. Dans cette formule R¿1? and R¿2? sont indépendamment sélectionnés dans le groupe formé par H, Me, halométhyle, groupes alkyle C¿2?-C¿3? saturés et non saturés, groupes alkyle C¿2?-C¿3? halogénés saturés et non saturés, groupes alkyle hydroxylés, ou R¿1? et R¿2? sont tous les deux sélectionnés parmi (CH¿2?)n, n représentant 4 ou 5, ou (CH¿2?)¿2?O(CH¿2?)¿2?; et R¿3? est sélectionné entre H, Me et des groupes alkyle C¿2?-C¿3? saturés et non saturés.

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