G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01) G01N 1/28 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2368007
The object of the present invention is to claim a composition which when added to a patient sample containing a target antigen in an acidic or formalin- containing transport medium neutralizes the acid and formalin while preserving immunoreactivity of the antigen allowing its detection. The composition comprises an amino glycol buffer, an amino acid, a salt, and a non-ionic detergent. A further object of the present invention is to claim a method of processing a sample by adding a composition comprising an amino glycol buffer, an amino acid, a salt, and a non-ionic detergent.
La présente invention porte sur une composition qui, ajoutée à un échantillon prélevé sur un patient et contenant un antigène cible dans un milieu de transport acide ou formolé, neutralise l'acide et le formol tout en préservant la réactivité immunologique de l'antigène permettant sa détection. Ladite composition comprend un tampon amino-glycolique, un acide aminé, un sel et un détergent non ionique. La présente invention porte également sur un procédé permettant de traiter un échantillon en y ajoutant une composition contenant un tampon amino-glycolique, un acide aminé, un sel et un détergent non ionique.
Genzyme Corporation
Gowling Lafleur Henderson Llp
LandOfFree
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