A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/12 (2006.01) A61K 31/44 (2006.01) A61K 31/50 (2006.01)
Patent
CA 2268640
The present invention is to provide a pharmaceutical composition for preventing or treating ischemic disease comprising a compound having endothelin antagonistic activity or a salt thereof in combination with a compound having activity for inhibiting Na-H exchange or a salt thereof, which shows remarkable prophylactic or therapeutic effect on ischemic disease and which serves to decrease remarkably the dosage of the individual effective components, and as a result, suppresses undesirable side effects observed in the case of administering the respective compounds singly.
Shiraishi Mitsuru
Wakimasu Mitsuhiro
Watanabe Toshifumi
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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