A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/06 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 47/36 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2458126
The invention concerns compositions and methods for reducing the decomposition rate of poly(carboxylic acids), such as hyaluronic acid. The compositions include at least one strong, stable chelating agent, preferably an organophosphorous compound such as diethylene triamine penta(methylene phosphonic acid). These biocompatible compositions are especially useful in the ophthalmic field. Also disclosed is a method of performing surgery on an eye including employing a hyaluronic acid material utilizing the inventive composition of the present invention.
L'invention concerne des compositions et des procédés de réduction de la vitesse de décomposition d'acides poly(carboxyliques), tels que l'acide hyaluronique. Ces compositions comprennent au moins un agent chélateur stable fort, de préférence un composé organophosphoré tel que l'acide diéthylènetriamine-penta-(méthylène-phosphonique). Ces compositions biocompatibles sont particulièrement utiles dans le domaine de l'ophtalmologie. L'invention concerne également une méthode destinée à réaliser une chirurgie sur un oeil et consistant à utiliser une substance à base d'acide hyaluronique comprenant la composition de la présente invention.
Ioltech
Novartis Ag
Smart & Biggar
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