Composition for sustained release of an agent

Details Composition for sustained release of an agent Composition for sustained release of an agent

A - Human Necessities

61

K

A61K 9/54 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/18 (2006.01) A61K 38/21 (2006.01) A61K 38/27 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2230494

Composition for the sustained release of a biologically active agent in vivo. The composition comprises microcarriers containing a first solid-phase biocompatible material and a biologically active agent, wherein said microcarriers sustain in vivo release of the biologically active agent. The composition also contains particles of a second biocompatible solid-phase material wherein the second solid-phase material further sustains the in vivo release of the biologically active agent. The invention also relates to a method for sustaining effective serum levels of a biologically active agent in a subject, including forming an injectable dose containing an effective amount of a biologically active agent, wherein the agent is contained in a microcarrier, with a release-period sustaining amount of a solid-phase material. The method further includes administering the injectable dose to the subject.

Composition permettant la libération prolongée d'un agent biologiquement actif in vivo. La composition comprend des microporteurs renfermant un premier matériau biocompatible en phase solide et un agent biologiquement actif. Ces microporteurs entretiennent la libération in vivo de l'agent biologiquement actif. En outre, la composition contient des particules constituées d'un second matériau biocompatible en phase solide, qui entretient lui aussi la libération in vivo de l'agent biologiquement actif. On décrit par ailleurs un procédé relatif à la libération de taux sériques efficaces d'un agent biologiquement actif chez un sujet, y compris la préparation d'une dose injectable contenant un agent biologiquement actif en quantité efficace que renferme un microporteur, et un matériau en phase solide en quantité capable d'entretenir une période de libération. Le procédé concerne également l'administration de la dose injectable au patient.

Affiliated with

Also associated with

Rating

Composition for sustained release of an agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Composition for sustained release of an agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition for sustained release of an agent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1532250