A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2740857
The present invention relates to a composition for targeting dendritic cells. In particular, the present invention relates to a composition comprising: a) one or more antigens; b) an anti-DC-SIGN immunoglobulin single variable domain; and c) a carrier which carries a) and b). The invention further relates to formulations, compositions and devices comprising such anti-DC-SIGN molecules and their use as a medicament and in the treatment of cancer, suitably melanoma.
La présente invention concerne une composition pour cibler des cellules dendritiques. En particulier, la présente invention concerne une composition comprenant : a) un ou plusieurs antigènes; b) un domaine variable unique dimmunoglobuline anti-DC-SIGN; et c) un porteur qui porte a) et b). Linvention concerne en outre des formulations, des compositions et des dispositifs comprenant de telles molécules anti-DC-SIGN et leur utilisation en tant que médicament et dans le traitement du cancer, de manière appropriée un mélanome.
Altin Joseph
Atmosukarto Ines
de Wildt Rudolf Maria
Parish Christopher
Price Jason
Domantis Limited
Lipotek Pty Ltd
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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