Composition for targeting, storing and loading of liposomes

B - Operations – Transporting – 32 – B

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167/139, 167/163

B32B 5/16 (2006.01) A61K 37/22 (1990.01)

Patent

CA 1297787

PATENT TLC 119A NOVEL COMPOSITION FOR TARGETING, STORING AND LOADING OF LIPOSOMES ABSTRACT The present invention describes a composition consisting of liposomes covalently or non-covalently coupled to the glycoprotein streptavidin. The streptavidin may additionally be coupled to biotinated proteins such as Immunoglobulin G or monoclonal antibodies. The liposomes of the invention may have a transmembrane potential across their membranes, and may be dehydrated. In addition, the composition may contain ionizable bioactive agents such as antineoplastic agents, and may be used in diagnostic assays.

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