Composition for the selective release of an active ingredient

Details Composition for the selective release of an active ingredient Composition for the selective release of an active ingredient

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2197234

The present invention discloses a composition comprising, in that order, (a) a core of a material swelling in water; (b) a resilient, water insoluble, water permeable layer; (c) a layer containing one or more active ingredients; and (d) a layer of a material that becomes water permeable in a predetermined aqueous medium, capable of rupturing upon the expansion of the core. Also disclosed is the use of said composition as a drug.

La présente invention a pour objet une composition comprenant, successivement: (a) un noyau constitué d'un matériau gonflant dans l'eau; (b) une couche en un matériau élastique, laissant passer l'eau et insoluble dans l'eau; (c) une couche contenant au moins un principe actif; et (d) une couche en un matériau devenant perméable à l'eau dans un milieu aqueux prédéterminé, qui est susceptible de se rompre sous l'effet de l'expansion du noyau. L'invention a aussi pour objet son utilisation en tant que médicament.

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