Composition for the treatment of lung disease

Details Composition for the treatment of lung disease Composition for the treatment of lung disease

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 31/395 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2184385

Disclosed are pharmaceutical compositions for the treatment of lung disease, and in particular Cystic Fibrosis, comprising a substituted azetidinone of general formula (I), which have been found to be potent elastase inhibitors and a (F)-actin shortening protein, such as gelsolin.

Cette invention concerne des compositions pharmaceutiques destinées au traitement de la pneumopathie et plus particulièrement de la mucoviscidose, ces compositions comprenant une azétidinone substituée de formule (I) dont on a découvert le rôle d'inhibiteur puissant de l'élastase, et une protéine raccourcissant la (F)-actine, telle que la gelsoline.

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