A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/50 (2006.01) A61K 31/501 (2006.01) C07D 403/04 (2006.01)
Patent
CA 2347939
Disclosed is a pharmaceutical composition for modulating immunity, which comprises a benzimidazole, represented by the following general formula (I), a 3H tautomer, an optically active enantiomer or a pharmaceutically acceptable acid-addition salt thereof wherein, R represents an alkyl group having 1 to 5 carbon atoms, a hydroxyphenyl group or a methoxyphenyl group. This pharmaceutical composition is useful for treating cytokine-related diseases such as rheumatism, inflammation and allergy: (see formula I)
La présente invention concerne une composition de médicament immunomodulateur contenant un benzimidazole représenté à l'aide de la formule générale (I) (dans laquelle R représente un alkyle en C1-C5, un hydroxyphényle ou un méthoxyphényle), ou par un tautomère 3H, un énantiomère optiquement actif ou un sel d'addition acide de ce benzimidazole, acceptable sur le plan pharmaceutique. Cette composition est utile en tant que remède dans les troubles associés à la cytokine tels que le rhumatisme, l'inflammation ou l'allergie.
Matsumori Akira
Matsumori Akira
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Toray Industries Inc.
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