Composition for topical administration comprising an...

A - Human Necessities – 61 – P

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A61P 37/06 (2006.01) A61K 31/435 (2006.01) A61K 31/436 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/535 (2006.01) A61K 38/13 (2006.01) A61K 45/06 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2452372

The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2 inhibitor contains a tricyclo compound as shown by the general formula (I) or pharmaceutically acceptable salt thereof. The present invention further provides a method for treating inflammations and/or infections comprising topical administration of an effective amount of an interleukin 2 inhibitor and an antimicrobial agent to a subject in need of the treatment of inflammations and/or infections.

La présente invention porte sur une composition pour administration directe comprenant un inhibiteur de l'interleukine 2 et un agent antimicrobien comme ingrédients actifs. L'inhibiteur de l'interleukine 2 contient un composé tricyclo tel qu'indiqué dans la formule générale (I) ou un sel de celui-ci, acceptable d'un point de vue pharmaceutique. La présente invention porte également sur un procédé de traitement d'inflammations et/ou d'infections qui consiste à administrer directement à un sujet nécessitant ce traitement une quantité efficace d'un inhibiteur de l'interleukine 2 et d'un agent antimicrobien.

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