Composition for treating cartilage disease

A - Human Necessities – 61 – K

Patent

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A61K 31/67 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2334815

This invention provides a pharmaceutical composition comprising a compound of formula (I) wherein ring A is an optionally substituted benzene ring; R is a hydrogen atom or an optionally substituted hydrocarbon group; B is an optionally esterified or amidated carboxyl group; X is -CH(OH)- or -CO-; k is 0 or 1; and k' is 0, 1 or 2, or its salt, which can be advantageously used as an agent for prevention and/or treatment of a cartilage disease.

L'invention porte sur une préparation pharmaceutique comportant un composé de formule (I) dans laquelle: le cycle A est un cycle benzène facultativement substitué; R est H ou un groupe hydrocarbure facultativement substitué; B est un groupe carboxyle facultativement estérifié ou amidé; X est -CH(OH)- ou -CO-; k est 0 ou 1; et k' est 0, 1 ou 2, ou sur l'un de ses sels pouvant avantageusement servir d'agent de prévention et/ou de traitement d'une maladie du cartilage.

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