Composition for treatment of joint disease

Details Composition for treatment of joint disease Composition for treatment of joint disease

A - Human Necessities

61

K

A61K 31/734 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2703158

The present invention provides a composition for treating a joint disease containing as an active ingredient thereof a monovalent metal salt of alginic acid for which the endotoxin level thereof has been lowered to an extent that does not substantially induce inflammation or fever. As a result, it is possible to provide a composition for treating a joint disease which has the effects of protecting cartilage from mechanical irritation, inhibiting degenerative changes in cartilage caused by wear and inflammation, repairing cartilage injuries, suppressing inflammation and pain of joint tissue, inhibiting degeneration of synovial tissue, and inhibiting osteochondral destruction.

L'invention porte sur une composition, pour le traitement d'une affection articulaire, qui est caractérisée par le fait qu'elle comporte, en tant qu'ingrédient actif, un sel de métal univalent d'acide alginique qui a un niveau d'endotoxine réduit dans une mesure telle qu'une inflammation ou un accès de fièvre n'est pas sensiblement induit. Il devient possible de proposer une composition de traitement d'une affection articulaire dont l'effet est de protéger un cartilage à l'encontre d'un stimulus mécanique, de prévenir la dégénérescence/la déformation d'un cartilage provoquée par un frottement ou une inflammation, de réparer la partie lésée d'un cartilage, de prévenir une inflammation ou une douleur dans un tissu articulaire, la dégénérescence d'un tissu synovial et la destruction d'un os ou d'un cartilage.

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