A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/47 (2006.01) A61K 31/517 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2675736
Disclosed are a pharmaceutical composition having excellent antitumor activity, and a method for treating a cancer. Specifically, excellent antitumor activity is achieved when 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7- methoxy-6-quinolinecarboxamide or an analogous compound thereof, a pharmacologically acceptable salt thereof or a solvate of any of them is used in combination with gemcitabine or erlotinib, a pharmacologically acceptable salt thereof or a solvate of any of them.
Cette invention concerne une composition pharmaceutique possédant une excellente activité antitumorale et un procédé de traitement du cancer. De manière spécifique, on obtient une excellente activité antitumorale lorsque du 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophénoxy)-7- méthoxy-6-quinoléinecarboxamide ou l'un de ses composés analogues, l'un de ses sels acceptables sur le plan pharmacologique ou l'un quelconque de leurs solvates est utilisé en combinaison avec de la gemcitabine ou de l'erlotinib, l'un de leurs sels acceptables sur le plan pharmacologique ou l'un quelconque de leurs solvates.
Eisai R&d Management Co. Ltd.
Fetherstonhaugh & Co.
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