Composition in the form of a spray containing a corticoid...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/12 (2006.01) A61K 31/573 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01)

Patent

CA 2631123

The invention relates to an anhydrous composition in the form of a spray containing a corticoid as an active pharmaceutical ingredient, preferably clobetasol propionate, and an oil phase in a physiologically-acceptable medium. The invention also relates to the method for preparing said composition and to the use thereof in dermatology. In an advantageous embodiment of the invention, the oil phase contains medium-chain triglycerides, one or more silicon oils and sweet almond oil. The inventive composition contains no vitamin D derivatives.

L' invention se rapporte à une composition anhydre sous forme de spray comprenant en tant qu'actif pharmaceutique un corticoïde, préférentiellement le propionate de clobetasol, et une phase huileuse dans un milieu physiologiquement acceptable, à son procédé de préparation, à son utilisation en dermatologie . Selon un mode de réalisation avantageux de l'invention, la phase huileuse contient des triglycerides a chaîne moyenne, une ou plusieures huiles de silicone et l'huile d'amande clouce. La composition de l'invention ne contient pas de derive de Vitamine D.

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