G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/00 (2006.01) G01N 27/62 (2006.01)
Patent
CA 2720051
The present invention relates to a method for detecting an ageing or a disease accompanied with a vascular disorder such as age-related macular degeneration, comprising measuring one or more of polypeptides comprising any of amino acid sequences shown in SEQ ID NOS: 1 to 21, mutants thereof, or fragments thereof in a biological sample from a subject, and also to a composition or kit for diagnosing an ageing or a disease accompanied with a vascular disorder such as age-related macular degeneration.
L'invention concerne une méthode de détection du vieillissement ou d'une maladie associée à un trouble vasculaire tel que la dégénérescence maculaire liée à l'âge, qui consiste à mesurer au moins un élément sélectionné à partir d'un polypeptide comprenant une séquence d'acides aminés décrite dans l'une quelconque des SEQ ID NO:1 à SEQ ID NO:21 contenues dans un échantillon biologique d'un patient, un mutant du polypeptide et un fragment du polypeptide. L'invention concerne également une composition ou une trousse de diagnostic de vieillissement ou de la maladie associé à un trouble vasculaire tel que la dégénérescence maculaire liée à l'âge.
Iwata Takeshi
Matsuno Kiyoshi
Tanahashi Kazuhiro
National Hospital Organization
Santen Pharmaceutical Co. Ltd.
Smart & Biggar
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