A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2078450
2078450 9213886 PCTABS00014 The composition, which is comprised of at least two antibodies, preferably monoclonal antibodies directed against the interleukin-2 receiver, includes an anti-p55 antibody and an anti-p75 antibody providing for the inhibition of the binding of interleukin-2 to its receiver. It concerns particularly the pairs 33B3.1/TU27, 33B3.1/Tic and 33B3.1/A41. The composition is useful as active agent against rejection of members and marrow grafting, against leucemia and positive CD25 lymphomas as well as against auto-immune pathologies such as type 1 diabetes, rheumatoid polyarthritis, ankylosing spondylarthritis, multiple sclerosis and myasthenia gravis.
Audrain Marie
Francois-Bendahou Christine
Jacques Yannick
Soulillou Jean-Paul
Fetherstonhaugh & Co.
Institut National de La Sante Et de La Recherche Medicale
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