Composition of tumor-associated peptides and related...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2739384

The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumor immune responses against gliomas.

L'invention concerne des peptides immunothérapeutiques et leur utilisation en immunothérapie, en particulier l'immunothérapie du cancer. L'invention concerne également des épitopes peptidiques de lymphocytes T auxiliaires, seuls ou combinés à d'autres peptides associés à une tumeur, qui servent de principes actifs pharmaceutiques de compositions de vaccin qui stimulent des réponses immunitaires anti-tumorales. En particulier, la composition de peptides selon l'invention peut être utilisée dans des compositions de vaccin pour éliciter des réponses immunitaires anti-tumorales dirigées contres des gliomes.

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