Composition of tyrosine and polymerised allergen

A - Human Necessities – 61 – K

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A61K 39/35 (2006.01) A61K 39/36 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2217388

A pharmaceutical composition comprising tyrosine and a polymerised allergen is prepared by (a) polymerising an allergen, (b) mixing an aqueous solution of the allergen with a solution of tyrosine in a strong aqueous acid, (c) neutralising the mixture of solutions, thereby co-precipitating tyrosine and polymerised allergen, and (d) optionally, mixing the product with a physiologically acceptable carrier.

Composition pharmaceutique comportant de la tyrosine et un allergène polymérisé, préparée (a) par polymérisation d'un allergène, (b) par mélange d'une solution aqueuse dudit allergène avec une solution de tyrosine dans un acide aqueux fort, (c) par neutralisation du mélange de solutions, ce qui entraîne une co-précipitation de la tyrosine et de l'allergène polymérisé, et (d) par mélange éventuel du produit avec un excipient physiologiquement acceptable.

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