A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/00 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 35/74 (2006.01) A61K 35/76 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61K 38/45 (2006.01) A61K 38/46 (2006.01)
Patent
CA 2156635
Composition for use in the treatment of tumors and the immunization of humans or animals comprising a synergistic association of cells, viruses, or bacteria expressing, transitorily, in organisms at least one gene for producing in vivo one or more immunomodulators, and viruses, or cells producing viruses, said viruses preferably infecting dividing cells of the treated organisms and carrying within their genome at least one gene whose expression in the dividing cells will cause their destruction.
Composition destinée à traiter les tumeurs d'organismes humains ou animaux et à immuniser ces organismes à l'encontre des tumeurs, ladite composition comprenant en association synergique: des cellules, des virus, ou des bactéries exprimant de manière transtoire dans l'organisme au moins un gène leur permettant de produire in vivo un ou plusieurs immunomodulateurs, et des virus, ou des cellules produisant des virus, lesdits virus infectant prérérentiellement les cellules en division de l'organisme traité et portant dans leur génome au moins un gène dont l'expression dans les cellules en division va entraIner leur mort.
Klatzmann David
Kourilsky Philippe
Mir Lluis
Roth Claude
Salzmann Jean-Loup
Assistance Publique-Hopitaux de Paris
Gowling Lafleur Henderson Llp
Institut National de La Sante Et de La Recherche Medicale (inser
Institut Pasteur
Universite Pierre Et Marie Curie
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