Compositions and compounds for use as molecular adjuvant for...

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 25/30 (2006.01) C07K 14/47 (2006.01) C07K 16/08 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2477268

Compounds are disclosed comprising molecular adjuvants having an antigen presenting cell-targeting ligand linked to a nicotine hapten. Methods are disclosed for employing the compounds as a nicotine vaccine for treatment or prevention of nicotine addiction.

L'invention concerne des composés comprenant des adjuvants moléculaires renfermant un ligand ciblant une cellule présentatrice d'antigène lié à un haptène de nicotine. L'invention concerne également des méthodes d'utilisation de ces composés comme vaccin contre la nicotine pour traiter ou prévenir la dépendance à la nicotine.

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