Compositions and elements containing triarylmethane leuco...

Details Compositions and elements containing triarylmethane leuco... Compositions and elements containing triarylmethane leuco...

G - Physics

01

N

150/14, 150/3

G01N 33/50 (2006.01) C12Q 1/28 (2006.01) G01N 21/78 (2006.01) G01N 31/22 (2006.01)

Patent

CA 1223512

- 0 - COMPOSITIONS AND ELEMENTS CONTAINING TRIARYLMETHANE LEUCO DYES AND METHODS USING SAME Abstract of the Disclosure A particular class of triarylmethane leuco dyes are useful in analytical compositions, elements and methods. These leuco dyes are triarylmethane compounds having an aromatic heterocyclic moiety attached to the central methane carbon and which, upon interaction with hydrogen peroxide, provide dyes having a maximum absorption at a wavelength equal to or greater than about 600 nm. Particularly useful leuco dyes have the structure: Image wherein R is a 5- to 15-membered aromatic heterocyclic moiety; and R' and R" are independently open chain or cyclic amines. These compounds are useful for providing detectable dyes in compositions and elements useful for detection of hydrogen peroxide or other analytes which react to produce hydrogen peroxide in aqueous liquids, e.g. biological fluids.

458834

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