C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) A61K 35/30 (2006.01) A61K 35/32 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2442915
The present invention provides compositions comprising notochord enriched media and/or one or more factors derived therefrom. Such compositions are useful for enhancing the production of proteoglycan in cells or animals in need thereof, for example for treating degenerative disc disease. The notochord enriched media is preferably obtained from a nonchondrodystrophic animal.
L'invention concerne des compositions comprenant des milieux enrichis en notocorde et/ou un ou plusieurs facteurs dérivés de ceux-ci. De telles compositions sont utilisées pour accroître la production de protéoglycane dans des cellules ou chez des animaux qui en nécessitent, par exemple, pour le traitement de dégénérescence discale. Le milieu enrichi en notocorde est obtenu de préférence à partir d'un animal non chondrodystrophique.
Erwin W. Mark
Inman Robert
Salo Paul T.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Health Network
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